Argentina's a large country, but with two weeks to spend, you can get to know several regions in one trip. On these five unique itineraries, you'll sail around glaciers in Patagonia, road-trip through the colorful scenery of the northwest, sip locally produced wine in Mendoza, and hike through the jungle to the awe-inspiring waterfalls of Iguazú.

Itinerary #1: El Calafate, Bariloche & Salta

On this two-week tour, you'll visit several of Argentina's most popular highlights, including the glaciers at El Calafate, the bright blue lakes in the region of Bariloche, and the colorful desert landscapes around Salta in the country's northwest.

View from the hiking trail in Nahuel Huapi National Park, outside Bariloche
View from the hiking trail in Nahuel Huapi National Park, outside Bariloche
Day Highlights Overnight
Day 1 Arrival in Buenos Aires - Explore the City Buenos Aires
Day 2 Fly from Buenos Aires to El Calafate El Calafate
Day 3 Perito Moreno Boat & Walking Tour El Calafate
Day 4 Punta Bandera Harbor - Glacier Boat Tour El Calafate
Day 5 From El Calafate to Bariloche Bariloche
Day 6 Bariloche History & Nature Tour Bariloche
Day 7 Boat Tour of Tristeza Sound Bariloche
Day 8 Fly from Bariloche to Salta - Pick-Up Rental Car Salta
Day 9 Self-Drive from Salta to Cafayate Cafayate
Day 10 Self-Drive from Cafayate to Cachi Cachi
Day 11 Self-Drive from Cachi to Salta Salta
Day 12 Self-Drive from Salta to Purmamarca Purmamarca
Day 13 Self-Drive from Purmamarca to Salta Salta
Day 14 Fly from Salta to Buenos Aires - Departure  


Begin the adventure in Buenos Aires, where you'll tour the city, stopping at key attractions like the Casa Rosada (Presidential Palace) and the historic neighborhood of San Telmo. Then fly south to El Calafate the next day, where you'll see the massive Perito Moreno glacier up close and go on a boat tour through the icy waters of Parque Nacional Los Glaciares (Glaciers National Park). Continue onto Bariloche in the Lake District on day six, enjoying traditional chocolates in town and going on a boat tour of Tristeza Sound.

Midway through the trip, you'll fly to the colonial city of Salta and pick up a rental car to explore the northern region of Argentina at your own pace. Side trips from Salta include a self-guided wine trip of the nearby Cafayate wine region, where you'll taste a range of locally produced wines at local wineries, and another to Cachi, where indigenous and Spanish traditions are evident in details from architecture to food. Continue onto Purmamarca, located at the base of Jujuy's famed seven-colored mountain. Finish up with one last evening in Salta, where you'll feast on empanadas and hear folkloric music, before catching a flight back to Buenos Aires. Learn more

Itinerary #2: Vistas & Vintners Grand Tour

See some of Argentina's top destinations, including Buenos Aires, the wine-producing region of Mendoza, Salta and the northwest, and the gaucho town of San Antonio de Areco, on this two-week trip plan.

Vineyards in the shadow of the Andes, Mendoza, Argentina
Vineyards in the shadow of the Andes, Mendoza, Argentina
Day Highlights Overnight
Day 1 Welcome to Buenos Aires! Buenos Aires
Day 2 Buenos Aires Walking Tour & Tango Lesson Buenos Aires
Day 3 Buenos Aires Full-Day Bicycle Tour Buenos Aires
Day 4 Off to Bariloche Bariloche
Day 5 Hiking Bariloche Bariloche
Day 6 Bariloche Adventure Bariloche
Day 7 Bariloche to Mendoza Chacras de Coria
Day 8 Mendoza Full-Day Wine Tour & Cooking Class Chacras de Coria
Day 9 Free Day at Chacras de Coria Chacras de Coria
Day 10 Fly from Mendoza to Salta Salta
Day 11 Salt Flats and Quebrada de Humahuaca Purmamarca
Day 12 Return to Salta - Wine Tour Salta
Day 13 The Pampas San Antonio de Areco
Day 14 Pampas - Buenos Aires & Farewell Argentina  


The trip begins in Buenos Aires, where you'll hit the ground running with several active adventures, including a tango lesson and a full-day bicycle tour of the city. Then you'll catch a flight to Bariloche for hiking in the mountains high above Lago Nahuel Huapi lake and wandering the streets of the waterfront Swiss-style town filled with chocolate shops. Go kayaking on another lake, Lago Mascardi, or opt for a mountain biking trip into the foothills of the Andes that ends at a local microbrewery for cold drinks. 

Fly to Mendoza, the heart of Argentina's wine scene, to visit several wineries for tours, tastings, and leisurely lunches with wine pairings. You'll take a cooking class one day and road-trip up into the Andes on another, picnicking on the shores of the bright blue lake at Portrerillos. Back in the city, dine at 1884, Francis Mallmann's signature restaurant in Mendoza, famous for its grilled meats and produce—and, of course, a great wine selection. You'll fly from Mendoza to Salta to discover the natural beauty of the Quebrada de Humahuaca landscapes and see expansive salt flats, spending the night in scenic Purmamarca. Sample dry white wines made in the region before flying back to Buenos Aires and driving out to the gaucho town of San Antonio de Areco. Spend the night in the old countryside estate-turned-boutique hotel, El Ombú de Areco, before heading back to the city for the trip's end. Learn more

Itinerary #3: Epic Argentina Road Trip

Hit the road for this two-week adventure around Argentina's scenic north, including stops in picturesque Tilcara, the salt flats outside of Salta, and the wine-growing region of Cafayate.

The Quebrada de Humahuaca, near Tilcara, Argentina
The Quebrada de Humahuaca near Tilcara, Argentina
Day Highlights Overnight
Day 1 Welcome to Buenos Aires! Buenos Aires
Day 2 Buenos Aires Walking Tour & Tango Lesson Buenos Aires
Day 3 Buenos Aires Full-Day Bicycle Tour Buenos Aires
Day 4 Off to Bariloche Bariloche
Day 5 Hiking Bariloche Bariloche
Day 6 Bariloche Adventure Bariloche
Day 7 Bariloche to Mendoza Chacras de Coria
Day 8 Mendoza Full-Day Wine Tour & Cooking Class Chacras de Coria
Day 9 Free Day at Chacras de Coria Chacras de Coria
Day 10 Fly from Mendoza to Salta Salta
Day 11 Salt Flats and Quebrada de Humahuaca Purmamarca
Day 12 Return to Salta - Wine Tour Salta
Day 13 The Pampas San Antonio de Areco
Day 14 Pampas - Buenos Aires & Farewell Argentina  


Get into the swing of things in Buenos Aires, where your trip begins. You'll fly up to Salta and pick up a rental car to start exploring the north, starting with the pre-Inca fortification of Pucará de Tilcara and the village of Tilcara in the province of Jujuy. Explore the Salinas Grandes salt flats and the ghost towns nearby, continuing onward to the otherworldly red rock structures around San Antonio de los Cobres, where you'll spend a night. Tolar Grande, a tiny village in the striking landscape of the Puna de Atacama, is the next day's destination: make sure your camera battery is fully charged, as you'll be stopping along the way for photo ops.

Drive to Antofalla, passing the volcanic pyramid of Cono de Arita on the way. You'll stay in a family home near the salt flats of Antofalla on day eight, continuing to the small highland village of El Peñon. It's your base for side trips to Piedra Pomez, also known as the Pumice Stone Field, a vision of white volcanic rocks, and Carachi Pampa, a young volcano. Getting thirsty? Head to the wine region of Cafayate to try local varietals and pull over for views of Quebrada de las Conchas, a valley of red canyons. After a quick detour through Los Cardones National Park, famous for its giant cactus plants, before heading back to Buenos Aires. Learn more

Itinerary #4: Highlights of Northern Argentina

Sip wine by the Andes, hike through gorges and desert scenery, and see the waterfalls of Iguazú on this two-week itinerary around Argentina's northern region.

The waterfalls of Iguazú
The waterfalls of Iguazú
Day Highlights Overnight
Day 1 Arrival in Buenos Aires - Explore the City Buenos Aires
Day 2 Buenos Aires City Tour - Dinner & Tango Show Buenos Aires
Day 3 San Antonio de Areco Estancia Tour Buenos Aires
Day 4 Fly from Buenos Aires to Mendoza Mendoza
Day 5 Mendoza Wine Tour Mendoza
Day 6 Barbeque Cooking Class Mendoza
Day 7 Mendoza Free Day Mendoza
Day 8 Fly from Mendoza to Salta Salta
Day 9 Cafayate Tour & Wine Tasting Salta
Day 10 Quebrada de Humahuaca Excursion Salta
Day 11 Fly from Salta to Iguazú Iguazu Falls
Day 12 Explore Iguazú Falls (Argentine Side) Iguazu Falls
Day 13 Explore Iguazú Falls (Brazilian Side) Iguazu Falls
Day 14 Fly from Iguazu Falls to Buenos Aires - Departure  


On this journey to the west and north of Argentina, you'll begin in Buenos Aires, getting acclimated in the city before making the short side trip to the gaucho town of San Antonio de Areco for a taste of traditional countryside life. Head back to Buenos Aires to board a quick domestic flight to Mendoza. In the wine-growing region, you'll taste Malbec at the place where it's made, going on tastings and tours at several wineries, taking a cooking class where you'll learn the secrets behind the classic Argentine asado (barbecue), and driving up into the foothills of the Andes to take in views of snow-capped mountains and condors flying overhead.

Moving onto Salta, the next destination on the itinerary, you'll ride a cable car up to Cerro San Bernardo for sweeping views of the region you'll be exploring for the next few days. Sip Torrontés, a dry, floral white wine, in nearby Cafayate wine region before checking out the unusual rock formations in the Quebrada del Río de las Conchas. On day ten, explore the beautiful Quebrada de Humahuaca, an arid desert valley famous for its colorful cliffs and gorges, ending up at  La Paleta del Pintor (The Painter's Palette), so named for its vibrantly hued mountains. Finish the tour in the far north of the country, where the immense waterfalls of Iguazú, straddling the border of Argentina and Brazil, await. You'll spot exotic butterflies and monkeys while hiking in the national park—and if you're feeling extra adventurous, take an exhilarating boat ride to the base of the falls. Fly back to Buenos Aires for one last night on the town in the capital city. Learn more

Itinerary #5: Best of Argentine Patagonia 

See the best of Argentina's side of Patagonia on this two-week trip plan that includes a cruise on the Beagle Channel, trekking on glaciers, and hiking in windswept national parks.

  Save Download Preview Les Eclaireurs lighthouse island in the the Beagle Channel
Les Eclaireurs lighthouse island in the Beagle Channel
Day Highlights Overnight
Day 1 Arrival in Buenos Aires - Explore the City Buenos Aires
Day 2 Fly from Buenos Aires to El Calafate El Calafate
Day 3 El Calafate to Los Glaciares National Park - Perito Moreno Glacier Hike El Calafate
Day 4 Free Day in El Calafate El Calafate
Day 5 El Calafate to El Chaltén El Chalten
Day 6 Hike to Mt. Fitz Roy El Chalten
Day 7 Hike to Mirador Cerro Torre El Chalten
Day 8 Free Day in El Chaltén El Chalten
Day 9 El Chaltén to El Calafate El Calafate
Day 10 Fly from El Calafate to Ushuaia - Explore the City Ushuaia
Day 11 Trekking & Canoeing in Tierra del Fuego National Park Ushuaia
Day 12 Beagle Channel Cruise Ushuaia
Day 13 Penguins on Isla Martillo & Estancia Harberton Ushuaia
Day 14 Fly from Ushuaia to Buenos Aires - Departure  


Start in Buenos Aires, then fly to El Calafate on day two. You'll trek on Perito Moreno glacier the next day, part of Los Glaciares National Park, and see massive pieces of ice falling off and splashing into the water below. On the three-hour drive to El Chaltén, nicknamed "hiker's paradise," you'll enjoy incredible views of Mount Fitz Roy from the car window. You'll hike to its summit the next day, and then to Mirador Cerro Torre on day seven, ending up at the glacial lake of Laguna Torre.

Head back to El Calafate and catch a flight to Ushuaia, the southernmost city in the world, in Tierra del Fuego. You'll go trekking and canoeing in Tierra del Fuego National Park, then take a cruise around the Beagle Channel. Highlights on the boat tour include a sea lion colony, Les Eclaireurs lighthouse, and a quick stop at an island for a short and scenic hike. The end of the trip is all about penguins: on a full-day excursion to Isla Martillo and Estancia Harberton, you'll see hundreds or even thousands of penguins in their natural habitat. Board a flight back to Buenos Aires the next day to wrap up the trip. Learn more

More Great 14-Day Argentina Itineraries

Looking for more inspiration for your Argentina trip? Check out these other 14-day Argentina itineraries, ranging from active, to cultural, to luxury, or family-friendly trips.

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Map of 2 Weeks in Argentina - 5 Unique Itinerary Ideas
Map of 2 Weeks in Argentina - 5 Unique Itinerary Ideas